Escherichia coli remains at the forefront of recombinant protein production, owing to its rapid growth, well-characterised genetics and the ease with which it can be genetically manipulated. The ...

Non-CHO cell expression systems gain traction as faster, more flexible alternatives for biologics manufacturing.

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

This important study analyzed the impact of amino acid homorepeats on protein expression and solubility in yeast and E. coli. The authors provided convincing evidence that hydrophobic and positively ...

The Expi293™ PRO Expression System is a high-performance transient HEK293 mammalian protein expression platform designed to help researchers express more proteins faster, at higher yields, and with ...

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...

Proteomics-informed, genome-edited CHO design increased productivity up to three-fold and titers two-fold, strengthening CLD for novel biologics and biosimilars. Extended culture robustness was ...

Impact of lorlatinib dose modifications on adverse event outcomes in the phase 3 CROWN study. RC108 in combination with furmonertinib in patients with locally advanced or metastatic EGFR-mutated ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

Fruit flies, mice, zebrafish, yeast and the tiny worm C. elegans are model organisms that have carried modern biology on ...