Estrogens, traditionally viewed as female hormones, are now recognised as critical regulators of male reproductive function. In the testis, local synthesis of 17β-estradiol by aromatase in Leydig ...

Leptin, an adipocyte-derived hormone, serves as a critical link between energy homeostasis and reproductive function. Acting centrally, leptin modulates hypothalamic centres that regulate gonadotropin ...

AI-powered model predicts biological aging through steroid pathways, highlighting key biomarkers like cortisol. Study: Biological age prediction using a DNN model based on pathways of steroidogenesis.

Mitochondrial dysfunction and redox imbalance are central drivers of cardiovascular disease, contributing to impaired bioenergetics, oxidative stress, ...

Endocannabinoids (ECs) and steroid hormones are endogenous substances that each play a central role in human stress response regulation. These regulators’ concentration fluctuates significantly ...

Steroid hormones are among the most widespread aquatic micropollutants. They are harmful to human health, and they cause ecological imbalances in aquatic environments. Researchers investigated how ...