Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...
Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment has been the focus of a 30-year research question. New work from the Crick ...
A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...