PITTSBURGH, Sept. 20 -- A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible ...

CAMBRIDGE, MA -- When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after ...

This pathway, the "anticipatory unfolded protein response, or a-UPR," ultimately causes the cell to swell, leak and die. "Even though we identified the initial steps in the a-UPR pathway that kills ...

A new eGastroenterology study reveals that massive hepatic necrosis in acute liver failure results from immune-mediated hepatocyte death and multiple cell death pathways, with liver progenitor ...

Adverse events associated with escalating imatinib versus switching to dasatinib in patients with chronic myelegenous leukemia ...

To uncover the inflammatory pathways involved in cell injury and death, Kenneth Rock at the University of Massachusetts and colleagues injected necrotic cells into mice deficient in various toll-like ...

What are the molecular events, in particular membrane trafficking events, that are involved in the degradation of apoptotic cells? Organelles in the endocytic pathway, such as early endosomes and ...