A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that ...

A protein, TDP43, previously linked to dementia and ALS, has been found to control DNA repair. Researchers say abnormal ...

Antisense oligonucleotides (ASOs), used to treat genetic diseases, can affect how cells repair damage to their DNA. This is ...

Researchers at the University of Bath have discovered how DNA damage caused by a faulty DNA protection and repair system can lead to neurodegenerative disorders such as motor neuron disease (MND).

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

Proteins PIF1 and PCNA gather at sites of DNA damage in SETX-deficient cells, indicating activation of the BIR repair system. LA JOLLA, CA—The DNA inside our cells is constantly being damaged, and one ...

Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy);(2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

Researchers at Houston Methodist have discovered that a protein tied to neurodegenerative conditions such as dementia and amyotrophic lateral sclerosis (ALS) also helps control a critical DNA repair ...