How p53 mutations drive immunotherapy resistance—and a path to overcome it

Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, but many tumors remain resistant. A new study from ...
News-Medical.Net

Study reveals how p53 mutations cause tumors to resist cancer immunotherapy

Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, but many tumors remain resistant. A new study from ...
Mirage News

CDI Unveils P53 Mutation's Role in Immunotherapy Resistance

Immune checkpoint blockade (ICB) therapy has transformed cancer treatment, but many tumors remain resistant. A new study from researchers at the ...
ascopubs.org

Stepping Up With Immune Checkpoint Blockade: More Combinations and Fewer Contraindications

Translating Cancer Science Into Cancer Care: Using Serious Illness Communication Frameworks to Deliver High-Quality Person-Centered Care in Neuro-Oncology Immune checkpoint inhibitors (ICIs) have ...
ascopubs.org

DNA Damage Response Alterations and Immune Checkpoint Blockade Outcomes Across Multiple Cancers

Phase II Study of Adavosertib in Patients With Tumors Containing BRCA1 and BRCA2 Mutations: Results From the NCI-MATCH ECOG-ACRIN Cancer Research Group (EAY131) Subprotocol Z1I We integrated ...