Amyloid-β (Aβ) peptide, the primary constituent of senile plaques in Alzheimer's disease (AD), is generated by β-secretase- and γ-secretase-mediated sequential proteolysis of the amyloid precursor ...
Scientists once hoped that blocking β-secretase would slow or prevent Alzheimer’s disease. Then came the rude awakening. The inhibitors caused the very thing they were supposed to prevent—cognitive ...
CHARLOTTE, NC--(Marketwired - Feb 17, 2015) - BACE, a global manufacturer of balers and compactors for the recycling and waste-disposal industries, has entered a strategic investment partnership with ...
Eli Lilly and AstraZeneca today announced that they will end two ongoing Phase 3 trials of lanabecestat, a small-molecule BACE inhibitor the two companies have been developing jointly since 2014.
CHARLOTTE, NC--(Marketwired - Nov 4, 2014) - BACE, a global manufacturer of balers and compactors for the recycling and waste-disposal industries, has appointed Paul Domanico to the position, Director ...
The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates ...
CHARLOTTE, N.C.--(BUSINESS WIRE)--BACE, LLC, a leading global equipment manufacturer, technology innovator and national service provider for the recycling and waste management industry, announces the ...
JAM Capital Partners has agreed to make an investment in BACE, a Charlotte, North Carolina-based maker of balers and compactors for the recycling and waste-disposal sectors. No financial terms were ...
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